Publications PDF Print E-mail
 
 

2015

 

 

Gocht T, Berggren E, Ahr HJ, Cotgreave I, Cronin MT, Daston G, Hardy B, Heinzle E, Hescheler J, Knight DJ, Mahony C, Peschanski M, Schwarz M, Thomas RS, Verfaillie C, White A, Whelan M
The SEURAT-1 approach towards animal free human safety assessment
ALTEX 32(1):9-24

 

 

2014

 

Holmgren G, Sjögren AK, Barragan I, Sabirsh A, Sartipy P, Synnergren J, Björquist P, Ingelman-Sundberg M, Andersson TB and Edsbagge J
Long-Term Chronic Toxicity Testing Using Human Pluripotent Stem Cell–Derived Hepatocytes
Drug Metab Dispos.42(9):1401-6

 

 

2013

 

Ulvestad M, Nordell P, Asplund A, Rehnström M, Jacobsson S, Holmgren G, Davidson L, Brolén G, Edsbagge J, Björquist P, Küppers-Munther B, Andersson TB.
Drug metabolizing enzyme and transporter protein profiles of hepatocytes derived from human embryonic and induced pluripotent stem cells
Biochem Pharmacol. 2013 Sep 1;86(5):691-702. Epub 2013 Jul 12

 

Jahnke HG1, Steel D, Fleischer S, Seidel D, Kurz R, Vinz S, Dahlenborg K, Sartipy P, Robitzki AA.
A novel 3D label-free monitoring system of hES-derived cardiomyocyte clusters: a step forward to in vitro cardiotoxicity testing
PLoS One. 2013 Jul 8;8(7):e68971

 

Sivertsson L1, Synnergren J, Jensen J, Björquist P, Ingelman-Sundberg M.
Hepatic differentiation and maturation of human embryonic stem cells cultured in a perfused three-dimensional bioreactor
Stem Cells Dev. 2013 Feb 15;22(4):581-94


 

2012

 

Simone Haupt, Jan Grützner, Marc-Christian Thier,Tobias Kallweit, Barbara Helen Rath, Iris Laufenberg, Michael Forgber, Jens Eberhardt, Frank Edenhofer, Oliver Brüstle
Automated selection and harvesting of pluripotent stem cell colonies
Biotechnology and Applied Biochemistry, 59: 77–87

 

Malin Darnell, Maria Ulvestad, Ewa Ellis, Lars Weidolf, Tommy B. Andersson
In vitro evaluation of major in vivo drug metabolic pathways using primary human hepatocytes and HepaRG cells in suspension and in a dynamic three-dimensional bioreactor system
Pharmacol Exp Ther. 2012 Oct;343(1):134-44

 

Maria Ulvestad, Malin Darnell, Espen Molden, Ewa Ellis, Anders Åsberg, and Tommy B. Andersson
Evaluation of organic anion-transporting polypeptide 1B1 and CYP3A4 activities in primary human hepatocytes and HepaRG cells cultured in a dynamic three-dimensional bioreactor system
J. Pharmacol Exp Ther. 2012 Oct;343(1):134-44

 

Jane Synnergren, Caroline Améen, Andreas Jansson and Peter Sartipy
Global transcriptional profiling reveals similarities and differences between human stem cell-derived cardiomyocyte clusters and heart tissue
Physiol Genomics. 2012 Feb 27;44(4):245-58.

 

Francesca Pistollato, Susanne Bremer-Hoffmann, Lyn Healy, Lesley Young and Glyn Stacey
Standardization of Pluripotent Stem Cell Cultures for Toxicity Testing
Expert Opin. Drug Metab. Toxicol. 2012 Feb;8(2):239-57

 

 

2011

 

Philipp Koch, Peter Breuer, Michael Peitz, Johannes Jungverdorben, Jaideep Kesavan, Daniel Poppe, Jonas Doerr, Julia Ladewig, Jerome  Mertens, Thomas Tüting, Per Hoffmann,Thomas Klockgether, Bernd O. Evert, Ullrich Wüllner and Oliver Brüstle
Excitation-induced ataxin-3 aggregation in neurons from patients with Machado–Joseph disease
Nature. 2011 Nov 23;480(7378):543-6


Silvia Colleoni, Cesare Galli, John Antony Gaspar, Kesavan Meganathan, Smita Jagtap, Jurgen Hescheler, Agapios Sachinidis and Giovanna Lazzari
Development of a Neural Teratogenicity Test Based on Human Embryonic Stem Cells: Response to Retinoic Acid Exposure
Toxicol Sci. 2011 Dec;124(2):370-7.

 

Peter Sartipy, and Petter Björquist
Concise Review: Human Pluripotent Stem Cell Based Models for Cardiac and Hepatic Toxicity Assessment
Stem Cells. 2011 May;29(5):744-8.